What is INAD?
Information on INAD from the National Organization of Rare Disorders (NORD) website
- Infantile neuroaxonal dystrophy (INAD) is an extremely rare, inherited degenerative disorder of the nervous system characterized by abnormalities of nerve endings (axon terminals) within the brain and spinal cord (central nervous system) and outside the central nervous system (peripheral nerves). In most cases, infants and children with INAD appear to develop normally until approximately 14 to 18 months of age, when they may begin to experience progressively increased difficulties in walking. In other cases, symptoms may begin at approximately six to eight months of age, at which time infants may experience delays or an arrest in the acquisition of skills requiring the coordination of mental and physical activities (delayed psychomotor development).
- The symptoms and physical characteristics associated with infantile neuroaxonal dystrophy are the result of swelling and degeneration of nerve endings (dystrophic axonal swellings or “spheroids”) within and without areas of the brain and spinal cord (central nervous system). In most cases, INAD is inherited as an autosomal recessive genetic trait.
Thank you to NORD for letting me use this information. Please visit their website for more resources, including how to purchase more information on INAD and other rare disorders, at www.raredisorders.org
Links to other INAD information sites
National Institute of Neurological Disorders and Stroke
NBIA Disorders Association Page
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